Localized Symptoms Of Cancer Disease (By Organ/System)

 


Localized signs arising from types of cancer may include symptoms localized to affected organs or systems. These are the signs associated with different types of cancer that occur in different parts of the body:

1. Respiratory system (lung cancer)

Most of the symptoms associated with lung cancer are related to breathing and chest discomfort. Some of its common symptoms include:

  • New persistent cough: A new cough that does not get better, or a change in a pre-existing cough.
  • Blood in sputum: This may indicate bleeding from the tumor.
  • Shortness of breath: Difficulty breathing or feeling short of breath with little exertion.
  • Chest pain: Pain that may be dull or sharp, worsening with deep breathing or coughing.
  • Wheezing: A whistling sound during breathing that is caused by blockage of the airways.
  • Hoarseness: voice changes, especially where the tumor presses on the vocal cords or laryngeal nerves.

2. Gastrointestinal System: Stomach, Colon And Pancreatic Cancer

Gastrointestinal cancer causes various signs and symptoms affecting digestion as well as bowel related problems. Some of them include:

  • Stomach pain: Stomach pain or discomfort is an ominous sign of stomach, pancreas and colon cancer.
  • Nausea and vomiting: This is one of the most common symptoms associated with gastrointestinal cancer, especially with colon cancer or cancer metastasizing to the liver.
  • Change in bowel habits: Diarrhea or constipation that lasts for some time or change in the shape and size of stool. Blood in the stool as a result of colon cancer can cause black, sticky stools or even bright blood-red stools.
  • Indigestion or difficulty swallowing: Difficulty swallowing (dysphagia) is common in cancer of the esophagus, stomach, or throat and is often associated with pain.
  • Unexplained weight loss: Weight loss without changing diet or activity levels.

3. Urinary System: Bladder, Kidney and Prostate Cancer

Cancer of the urinary system such as the bladder, kidneys or prostate may be associated with a variety of symptoms that are more related to urination and pelvic pain:

  • Painful urination: Pain or burning while urinating is common in bladder or prostate cancer.
  • Frequent urination: Especially at night, called nocturia, is a symptom of prostate or bladder cancer.
  • Blood in urine: Hematuria is a major symptom of bladder and kidney cancer.
  • Back pain: Persistent dull back pain or pain in the side could be kidney cancer.
  • Weak urine flow: Difficulty urinating or the presence of weak urine flow is common in men with prostate cancer.

4. Breast Cancer

The following symptoms characterize breast cancer: Changes in the breast or nipple or the way they feel.

  • Breast lump: This is usually the first symptom that develops—a lump that can be felt through the skin or found through imaging.
  • Changes in breast size or shape: mismatched swelling and asymmetry in one breast.
  • Nipple discharge: Especially if it's bloody or clear, it could be a sign of cancer.
  • Skin changes: Redness, puckering, or dimpling of the skin over the breast may be a sign of advanced breast cancer.
  • Breast pain: While breast cancer is not always painful, some women may experience pain, especially in the later stages.
  • Painful intercourse: This also occurs in cases of cervical or ovarian cancer.

6. Blood system (leukemia, lymphoma)


Cancers of the blood or lymphatic system have some non-specific symptoms for specific signs such as:

  • Swollen lymph nodes: Typically, lymph nodes in lymphoma may be non-tender and somewhat swollen that feel hard.
  • Bruises easily: Symptoms associated with leukemia or lymphoma can result from low platelet counts in the blood which can lead to dangerously abnormal bleeding or bruising.
  • An unexplained fever and night sweats: a common feature with lymphoma, leukemia, and other blood-related cancers. Some people like to turn pale and feel anemic due to low number of red blood cells.
  • Frequent infections: Low white blood cells from normal in leukemia patients lead to frequent infections.


7. Head And Neck Cancer (Oral, Throat, Nose And Sinus Cancer)

Symptoms of head and neck cancer can vary depending on the nature of the tumor.
For example:

  • Throat pain or difficulty swallowing: May be a sign of cancer of the throat, esophagus, or mouth, especially if they persist or are painful.
  • Voice changes: Hoarseness or voice changes, primarily related to laryngeal cancer.
  • Mouth sores: Non-healing or bleeding sores may be a sign of oral cancer.
  • Nasal congestion and/or bleeding: Sinus discomfort, nose bleeding, or facial swelling may be a sign of nose or sinus cancer.
  • Lump in the neck: Swollen lymph nodes in the neck or hard lump in the neck, usually associated with head and neck cancer.

8. Skin Cancer

Skin cancer is a visible infiltration of the skin:

  • New or changing moles: New moles or changes in the appearance of existing moles are a clear sign of melanoma.
  • Itching, bleeding, or painful skin lesions: Skin lesions that are painful, bleeding, or not healing.
  • Red or dark areas: A persistent change in the color, shape, or texture of the skin over time.


Cancer is a complex and heterogeneous condition. Most of its symptoms vary greatly depending on the type of cancer, location of occurrence, and stage of the disease.
Common symptoms such as fatigue, weight loss, pain and fever may indicate a disease, one of which is cancer. Other more specific symptoms—such as a lump in the breast or blood in the urine or a persistent cough—often point to certain types of cancer and usually require further investigation.

If you or someone else is experiencing unexplained or persistent symptoms, it is important to visit a healthcare professional for proper diagnosis and investigation. Early detection greatly improves the treatment outcome of many cancers, so proper knowledge of these symptoms is important in fighting the disease.

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